Global Sickle Cell Anemia Drug Market Price Dosage And Clinical Pipeline Outlook 2024

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“Global Sickle Cell Anemia Drug Market, Price, Dosage and Clinical Pipeline Outlook 2024” Report Highlights:

Sickle Cell Disease Market Opportunity More Than US$ 350 Million
Price, Dosage and Sales Analysis of Key Drugs
Global Sickle Cell Anemia Drug Clinical Pipeline by Company and Phase
Global Sickle Cell Anemia Drug Clinical Pipeline: 40 Drugs
Marketed Sickle Cell Anemia Drugs: 4 Drugs
Future Aspects of Global Sickle Cell Disease Treatment Market

Sickle cell anemia - as the name suggests is a blood disorder widely identified by the sickle shaped red blood cells which are biconcave in shape in a healthy individual. It is one of the most prevalent inherited blood disorders globally. This disorder, cause by a specific gene mutation can severely hamper the quality of life of an affected individual.

The sickle shaped red blood cell restricts the uniform circulation of blood and oxygen within the circulatory system; sometimes even leading to the clogging of vessels, which can have serious health complications. Inspite of years of research, there is no known cure for sickle cell anemia. Fortunately, it has been observed that a combination of certain therapeutics along with antibiotics and vitamins has an enhanced efficacy in increasing the longevity and survival of patients - thus leading to the emergence of the sickle cell anemia therapeutics market.

Medications like antibiotics, antimetabolites, analgesics, vaccines and folic acids are the key therapeutics that contributes to more than 50% of the global market size followed by blood transfusion. Further, modern therapeutic methods like gene therapy and bone marrow transplant have also entered the segment in recent years, which currently contributes to a significant market size in the developed region of the world due to their exorbitant cost.

Market trends indicate that the entry of gene therapy and bone marrow transplant are bound to enhance the market growth in the coming years due to their high efficacy in treating sickle cell anemia. Research shows that bone marrow transplant can successfully be applied to treat sickle cell anemia completely along with gene therapy, which is also being considered as a potential cell therapy technique of the future. This discovery has garnered immense attention to the sickle cell therapy market segment globally.

It is evident that the growth of the sickle cell therapy market will indirectly impact the growth of other related market such as the immunosuppressant market, vaccine market, antimetabolites market and vitamin and antibiotic market. Among these, the immunosuppressant market is anticipated to show maximum growth in revenue, owing to the growth of the global sickle cell market.

Sickle cell anemia has been found to be a widely prevalent clinical indication in the African subcontinent with annual incidence being much higher than anywhere else in the world. However, when it comes to the market size, North America takes the lead with close to 40% of the global market size, followed by Europe. This is due to the region’s better accessibility to healthcare and infrastructure. Nonetheless, the rapid increase in the population during the forecast period in the Asia-pacific region is bound to make it the burgeoning market of the future.

KuicK Research Report on the “Global Sickle Cell Anemia Drug Market, Price, Dosage and Clinical Pipeline Outlook 2024” provides an insight into the current scenario of the sickle cell market around key regions of the world. The report provides an in depth analysis of the market with respect to market size, trends and latest market dynamics that might impact the future of the sickle cell market. A detailed cost analysis of therapeutics, growing demand for related therapeutics and several key details have been highlighted to gain an effective insight into the future projections and forecast of the lucrative market.

1. Sickle Cell Anemia - An Inherited Blood Disorder

1.1 Introduction

1.1.1 Signs and Symptoms of Sickle Cell Anemia

1.1.2 Types of Sickle Cell Disease

1.2 Antiquity of Sickle Cell Disease

2. Genetics and Diagnostics of Sickle Cell Disease

2.1 Genetic Mutations

2.2 Diagnostic Approaches for Sickle Cell Disease

2.2.1 Blood Test

2.2.2 Prenatal Testing

2.2.3 Newborn Screening

2.3 Cost Analysis of Sickle Cell Disease Diagnosis

3. Management Strategies for Sickle Cell Disease Treatment - Cost Analysis

3.1 Medication Methods

3.2 Transfusion

3.3 Bone Marrow Transplant

4. Total Annual Cost for Patients with Sickle Cell Disease

4.1 Fees for Hospitalization, Emergency Department and Professional Fees

4.2 Annual Fees for the care of an Adult Patient with Sickle Cell Disease

5. Advance Research for Treatment of Sickle Cell Anemia Disease

5.1 Introduction

5.2 Umbilical Cord Blood Transplant

5.3 Gene Therapy

6. Sickle Cell Anemia - Drug and Treatment Cost Analysis

6.1 Glutamine (Endari)

6.2 Hydroxycarbamide (Droxia, Hydrea)

6.3 Nicosan (Niprisan or Nix-0699)

6.4 Ibuprofen

7. Market Analysis of Sickle Cell Disease

7.1 Introduction

7.2 Sickle Cell Disease Market Size

8. Global Sickle Cell Anemia Drug Market Dynamics

8.1 Favorable Parameters

8.2 Challenges

9. Future Aspects of Global Sickle Cell Disease Treatment Market

10. Global Sickle Cell Anemia Drug Clinical Pipeline by Company and Phase

10.1 Sickle Cell Anemia Drug Clinical Pipeline Overview

10.2 Research

10.3 Preclinical

10.4 Phase-I

10.5 Phase-I/II

10.6 Phase-II

10.7 Phase-III

11. Marketed Sickle Cell Anemia Drug Clinical Insight

11.1 Glutamine (Endari and NutreStore)

11.2 Hydroxycarbamide (Siklos)

11.3 Hydroxycarbamide (Droxia, Hydrea, Litalir and OncoCarbide)

11.4 Nix 0699 (Hemoxin, Nicosan and Niprisan)

12. Competitive Landscape

12.1 BioMarin

12.2 Bluebird Bio Bluebird Bio

12.3 DeuteRx

12.4 Emmaus Medical

12.5 Gamida Cell

12.6 Global Blood Therapeutics

12.7 GlycoMimetics

12.8 Modus Therapeutics

12.9 Pfizer

12.10 Sancilio Pharmaceuticals

12.11 Sangamo Biosciences

Figure 1-1: Inheritance Pattern of Sickle Cell Anemia from One Generation to Next Generation

Figure 1-2: Historical Development of Sickle Cell Disease and its Therapeutic Approaches

Figure 2-1: Genetic Mutations which Occur at the Transcription and Translational Level

Figure 2-2: Pathophysiology of Sickle Cell Disease

Figure 2-3: Various Diagnostic Methods for Sickle Cell Disease

Figure 2-4: Price Analysis - Sickle Cell Diagnosis Cost with Insurance (US$), 2018

Figure 2-5: Price Analysis - Sickle Cell Diagnosis Cost without Insurance (US$), 2018

Figure 2-6: Price Analysis - CVS and Amniocentesis for Sickle Cell Anemia(US$), 2018

Figure 2-7: Global - Average NIPT Screening Cost by Technique (US$), 2018

Figure 3-1: Several Management Approaches for Sickle Cell Disease

Figure 3-2: Sickle Cell Disease - Treatment Cost Analysis by Medication (US$/Month), 2018

Figure 3-3: Acceptable Outcomes for Sickle Cell Disease Bone Marrow Transplant

Figure 3-4: Allogeneic and Autogenic Bone Marrow Transplant Cost (US$), 2018

Figure 4-1: Consultation Fees for Sickle Cell Disease (US$/Patient), 2018

Figure 4-2: Hospitalization Charges for Sickle Cell Disease (US$/Day), 2018

Figure 4-3: Price Analysis - Emergency Department Cost (US$/Patient), 2018

Figure 4-4: Emergency Department Professional Fees Billed by Severity (US$), 2018

Figure 4-5: Price Analysis - Average Hospital Charges (US$/SCD patient), 2018

Figure 4-6: Annual Cost Analysis for Tests Involved in Sickle Cell (US$/Patient), 2018

Figure 4-7: Expenditure on SCD Patient by Age (US$/Annum), 2018

Figure 5-1: Ongoing Research for the Development of Sickle Cell Disease Treatment

Figure 5-2: Umbilical Cord Blood Transplant Method for Sickle Cell Anemia

Figure 5-3: Cost Analysis - Umbilical Cord Blood Transplant (US$/Patient), 2018

Figure 5-4: Gene Therapy Method for Sickle Cell Disease Treatment

Figure 5-5: Gene Therapy - Estimated Cost of Therapy and Medication (US$/Patient),2018

Figure 6-1: Endari - Dosage by Body Weight (gram/Dose)

Figure 6-2: Endari - Dosage per day by Body Weight (gram/Day)

Figure 6-3: Endari - Packet Consumption (Number) per Dose by Weight

Figure 6-4: Endari - Packets Consumed (Number of Packets/Day)

Figure 6-5: Endari - Price Analysis for 5mg Tablet (US$/Packet), 2018

Figure 6-6: Droxia - Available Concentrations by type (mg/Tablet)

Figure 6-7: Droxia - Dosage Analysis by Weight (mg/kg)

Figure 6-8: Droxia - Price Analysis per 60 Tablet Packet (US$), 2018

Figure 6-9: Nicosan - Recommended Dosage in children and Adult (mg/Day)

Figure 6-10: Patent Approval Year in UK and US

Figure 6-11: Ibuprofen - Availability by concentration (mg and mg/ml)

Figure 6-12: Ibuprofen - Price of 6ml Intravenous Solution Vial (US$), 2018

Figure 6-13: Ibuprofen - Oral Capsule Price Analysis (US$), 2018

Figure 6-14: Ibuprofen - Price Analysis of Oral Suspension (US$), 2018

Figure 6-15: Ibuprofen - Price Analysis of Oral Tablets (US$/Packet), 2018

Figure 7-1: Burden of Rare Diseases in US and Globally (%)

Figure 7-2: Global - Incidence of Sickle Cell Disease (%), 2018

Figure 7-3: Global - Sickle Cell Anemia Childhood Survival Rates by Region (%), 2018

Figure 7-4: Global - Orphan Drugs Market Forecast (US$ Billion), 2016 - 2024

Figure 7-5: Global - Sickle Cell Disease Market Size (%), 2018

Figure 7-6: Global - Blood Disorders Market Size by Type (%), 2018

Figure 8-1: Favorable Growth Factors for the Sickle Cell Disease Treatment

Figure 8-2: Challenges to the Growth of Sickle Cell Disease Treatment

Figure 9-1: Global - Sickle Cell Disease Market Opportunity (US$ Million), 2018 -2024

Figure 10-1: Global - Sickle Cell Anemia Drug Pipeline by Phase (%), 2018 till 2024

Figure 10-2: Global - Sickle Cell Anemia Drug Pipeline by Phase (Number), 2018 till 2024

Figure 10-3: Global - Discontinued Sickle Cell Anemia Drug Pipeline by Phase (%),2018 till 2024

Figure 10-4: Global - Discontinued Sickle Cell Anemia Drug Pipeline by Phase (Number), 2018 till 2024

Table 3-1: Clinical Trials Addressing Transfusion Indications for Sickle Cell Disease

Table 5-2: Droxia - Dosage Analysis by Weight (mg/kg)

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Global Sickle Cell Anemia Drug Market Price Dosage And Clinical Pipeline Outlook 2024

Buy USD 20,000 Worth Of Reports (Single User/Multi User License) In USD 8000 Only

“Global Sickle Cell Anemia Drug Market, Price, Dosage and Clinical Pipeline Outlook 2024” Report Highlights:

Sickle Cell Disease Market Opportunity More Than US$ 350 Million

Price, Dosage and Sales Analysis of Key Drugs

Global Sickle Cell Anemia Drug Clinical Pipeline by Company and Phase

Global Sickle Cell Anemia Drug Clinical Pipeline: 40 Drugs

Marketed Sickle Cell Anemia Drugs: 4 Drugs

Future Aspects of Global Sickle Cell Disease Treatment Market

1. Sickle Cell Anemia - An Inherited Blood Disorder

1.1 Introduction

1.1.1 Signs and Symptoms of Sickle Cell Anemia

1.1.2 Types of Sickle Cell Disease

1.2 Antiquity of Sickle Cell Disease

2. Genetics and Diagnostics of Sickle Cell Disease

2.1 Genetic Mutations

2.2 Diagnostic Approaches for Sickle Cell Disease

2.2.1 Blood Test

2.2.2 Prenatal Testing

2.2.3 Newborn Screening

2.3 Cost Analysis of Sickle Cell Disease Diagnosis

3. Management Strategies for Sickle Cell Disease Treatment - Cost Analysis

3.1 Medication Methods

3.2 Transfusion

3.3 Bone Marrow Transplant

4. Total Annual Cost for Patients with Sickle Cell Disease

4.1 Fees for Hospitalization, Emergency Department and Professional Fees

4.2 Annual Fees for the care of an Adult Patient with Sickle Cell Disease

5. Advance Research for Treatment of Sickle Cell Anemia Disease

5.1 Introduction

5.2 Umbilical Cord Blood Transplant

5.3 Gene Therapy

6. Sickle Cell Anemia - Drug and Treatment Cost Analysis

6.1 Glutamine (Endari)

6.2 Hydroxycarbamide (Droxia, Hydrea)

6.3 Nicosan (Niprisan or Nix-0699)

6.4 Ibuprofen

7. Market Analysis of Sickle Cell Disease

7.1 Introduction

7.2 Sickle Cell Disease Market Size

8. Global Sickle Cell Anemia Drug Market Dynamics

8.1 Favorable Parameters

8.2 Challenges

9. Future Aspects of Global Sickle Cell Disease Treatment Market

10. Global Sickle Cell Anemia Drug Clinical Pipeline by Company and Phase

10.1 Sickle Cell Anemia Drug Clinical Pipeline Overview

10.2 Research

10.3 Preclinical

10.4 Phase-I

10.5 Phase-I/II

10.6 Phase-II

10.7 Phase-III

11. Marketed Sickle Cell Anemia Drug Clinical Insight

11.1 Glutamine (Endari and NutreStore)

11.2 Hydroxycarbamide (Siklos)

11.3 Hydroxycarbamide (Droxia, Hydrea, Litalir and OncoCarbide)

11.4 Nix 0699 (Hemoxin, Nicosan and Niprisan)

12. Competitive Landscape

12.1 BioMarin

12.2 Bluebird Bio Bluebird Bio

12.3 DeuteRx

12.4 Emmaus Medical

12.5 Gamida Cell

12.6 Global Blood Therapeutics

12.7 GlycoMimetics

12.8 Modus Therapeutics

12.9 Pfizer

12.10 Sancilio Pharmaceuticals

12.11 Sangamo Biosciences

Figure 1-1: Inheritance Pattern of Sickle Cell Anemia from One Generation to Next Generation

Figure 1-2: Historical Development of Sickle Cell Disease and its Therapeutic Approaches

Figure 2-1: Genetic Mutations which Occur at the Transcription and Translational Level

Figure 2-2: Pathophysiology of Sickle Cell Disease

Figure 2-3: Various Diagnostic Methods for Sickle Cell Disease

Figure 2-4: Price Analysis - Sickle Cell Diagnosis Cost with Insurance (US$), 2018

Figure 2-5: Price Analysis - Sickle Cell Diagnosis Cost without Insurance (US$), 2018

Figure 2-6: Price Analysis - CVS and Amniocentesis for Sickle Cell Anemia(US$), 2018

Figure 2-7: Global - Average NIPT Screening Cost by Technique (US$), 2018

Figure 3-1: Several Management Approaches for Sickle Cell Disease

Figure 3-2: Sickle Cell Disease - Treatment Cost Analysis by Medication (US$/Month), 2018